https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46824 in vivo lineage tracing to show that endometrial epithelium self-renews during development, growth, and regeneration and identified Axin2, a classical Wnt reporter gene, as a marker of long-lived bipotent epithelial progenitors that reside in endometrial glands. Axin2-expressing cells are responsible for epithelial regeneration in vivo and for endometrial organoid development in vitro. Ablation of Axin2⁺ cells severely impairs endometrial homeostasis and compromises its regeneration. More important, upon oncogenic transformation, these cells can lead to endometrial cancer. These findings provide valuable insights into the cellular basis of endometrial functions and diseases.]]> Thu 01 Dec 2022 10:59:01 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11354 Sat 24 Mar 2018 08:08:14 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17422 Sat 24 Mar 2018 08:01:38 AEDT ]]>